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Ephraim McDowell

Ephraim McDowell


Courtesy of McDowell House Museum, Inc.


Copyright 2002-2005 McDowell House Museum, Inc. All rights reserved.


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Picture3 Picture4phraim McDowell was born in Rockbridge County, Virginia on November 11, 1771, the ninth of eleven children.  He came to Kentucky as a boy of twelve when his father, Samuel, was asked to serve as one of the original judges for the land court.  His father was a veteran of the French and Indian War as well as a colonel during the American Revolution. After the family moved to Kentucky, the senior McDowell participated in the drafting of the Kentucky Constitution. Ephraim probably suffered hardships in these early years on the frontier, as did every one moving into this new land.  Historians think that the challenges he met at this time prepared him to think independently and act quickly later in his medical career.


Little is known about Ephraim's education in Kentucky.  In 1791 he went to Staunton, Virginia to begin an apprenticeship to Dr. Alexander Humphreys. From there he traveled to the University of Edinburgh, Scotland, the seat of medical learning at the time.  After 2 years in Scotland, he returned to open his practice of medicine in Danville in 1795.  In 1797 he purchased the apothecary shop.


Picture5 Picture6n 1802, Ephraim married Sarah Shelby, daughter of Isaac Shelby, the first governor of Kentucky.  They purchased a house adjacent to his shop.  The McDowells had nine children in this house, with five living to adulthood.


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"The Dawn of Abdominal Surgery"
by Dean Cormell, N.A.
Commissioned by Wyeth Laboratories, Philadelphia


In 1809, Dr. McDowell was called to Green County, Kentucky, to see a patient, Mrs. Jane Crawford.  Mrs. Crawford thought she was expecting twins.  Upon examination, Dr. McDowell realized she had an ovarian tumor.  After consultation with Mrs. Crawford, Dr. McDowell told her if she would travel to his home in Danville, he would perform the experimental surgery.  Dr. McDowell returned home.  Mrs. Crawford followed a few days later, sixty miles on horseback.  She rested several days after her arrival.


Then on Christmas morning, 1809, Dr. McDowell began his historic operation.  The ovarian tumor he removed from Mrs. Crawford weighed twenty-two and one-half pounds.  The surgery was performed without benefit of anesthetic or antisepsis, neither of which was known to the medical profession at the time. The whole procedure took 25 minutes.  Mrs. Crawford's surgery was successful.  She returned to her home in Green County twenty-five days after the operation and lived another thirty-two years.  This was the first successful removal of an ovarian tumor in the world.


McDowell did not immediately publish the results of this procedure.  He was not a prolific writer and waited until he had performed two further operations in 1813 and 1814 before publishing a report in 1817.  This was widely criticized in the English surgical literature.  There is evidence that he performed at least twelve operations for ovarian pathology.


"Having never seen so large a substance extracted, nor heard of an attempt, or success attending any operation such as this required, I gave to the unhappy woman…information of her dangerous situation…. The tumor…appeared full in view, but was so large we could not take it away entire…. We took out fifteen pounds of a dirty, gelatinous looking substance.  After which we cut through the fallopian tube, and extracted the sac, which weighed seven pounds and one half…. In five days I visited her, and much to my astonishment found her making up her bed."


McDowell E., Three cases of extirpation of diseased ovaria. Eclectic Repertory Anal Rev. 1817; 7:242-4.


One of Ephraim’s most famous patients was James K. Polk, for whom he removed a gall stone and repaired a hernia.  He was a member of the Philadelphia Medical Society in 1817 and a founder of Centre College in Danville, Kentucky, in 1819.  He was also well known for his generosity, and he performed considerable work for charity.


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The McDowell House and Apothecary Shop, as it appeared about 30 years ago. It was at this Danville, Boyle County, location that Dr. Ephraim McDowell (1771-1830) first performed his world-famous operation in 1809.  The home, built on land owned by Isaac Shelby, Kentucky's first governor and McDowell's father-in-law, has been restored and is open to the public.


Dr. McDowell continued his medical practice until his death from cramp colic in June 1830, at the age of fifty-eight.  Ironically, 21 years after his historic  surgery, the man who conquered abdominal surgery died of a ruptured appendix. And Jane Todd Crawford, his famous patient, outlived him and died at the ripe old age of 78.


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Bronze by Charles H. Niehaus, given in 1929.
Location: Senate connecting corridor, 2nd floor


In 1879 a monument was erected in his honor in Danville.  In 1929, the state of Kentucky donated a bronze statue of McDowell to the U.S. Capitol National Statuary Hall Collection.  Dr. McDowell was the great great grandfather of General John Campbell Greenway, whose statue was placed in the National Statuary Hall Collection by the state of Arizona in 1930.

 


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